ApoE-/- Fbn1C1041G/+
Description:
The Fbn1C1041G/+ mouse model crossbred with ApoE-/- mice and fed a high-fat diet, develops human-like advanced atherosclerotic unstable plaques, with plaque rupture, neovascularization, myocardial infarction.
| Date Model Generated | 11-Sep-2026 |
|---|---|
| Randomized | |
| Open for Collab. | YES |
| Species | Mouse |
| Genetic Modification | Transgenic |
| Genetic Background | C57BL/6J |
| Method of Modification | Homologous Recombination in ES cells |
| Disease Model | Atherosclerosis |
| Cre Recombinase | Not used |
| Zygosity | Heterozygote |
| Availability | Breeding pair |
Principal Investigator:
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