Animal Models | Cardio2Share Database

Name	Open for Collab.	Principal Investigator
apoA-I KO Mice with deficiency in the endogenous apolipoprotein A-I gene	YES	Emiel van der Vorst evandervorst@ukaachen.de
apoE KO Mice with deficiency in the endogenous ApoE gene. Develop spontaneous atherosclerosis	YES	Elena Butoi elena.dragomir@icbp.ro
apoE KO Mice with deficiency in the endogenous ApoE gene. Develop spontaneous atherosclerosis	YES	Ljubica Matic Ljubica.Matic@ki.se Karolinska Institute
apoE KO Mice with deficiency in the endogenous ApoE gene.	YES	Dimitris Kardassis kardasis@imbb.forth.gr 30-2810394549 Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology of Hellas
apoE KO Mice with deficiency in the endogenous ApoE gene	NO	Emiel van der Vorst evandervorst@ukaachen.de
ApoE-/- Fbn1C1041G/+ The Fbn1C1041G/+ mouse model crossbred with ApoE-/- mice and fed a high-fat diet, develops human-like advanced atherosclerotic unstable plaques, with plaque rupture, neovascularization, myocardial infarction.	YES	Lynn Roth lynn.roth@uantwerpen.be
Bmx-Cre An inducible cre deleter under the control of the BMX non-receptor tyrosine kinase promoter.	YES	Emiel van der Vorst evandervorst@ukaachen.de
BMX-CreERT2 tamoxifen-Inducibe, arterial EC-specific Cre	YES	Johannes Schmid johannes.schmid@meduniwien.ac.at
Cre-ERT2 Mice with a tamoxifen-inducible gene recombination system that fuses Cre recombinase to a mutant estrogen receptor ligand-binding domain (ERT2)	YES	Emiel van der Vorst evandervorst@ukaachen.de
Fbn1C1041G/+ The Fbn1C1041G/+ mouse model, which mimics Marfan syndrome, when crossbred with LDL receptor-deficient (LDLR-/-) or apoE-deficient (ApoE-/-) mice and fed a high-fat diet, develops human-like advanced atherosclerotic unstable plaques, characterized by exacerbated atherosclerosis, with larger... more	YES
Ksp-Cre Mice expressing the Cre recombinase specifically in kidney	YES	Emiel van der Vorst evandervorst@ukaachen.de
LDLr KO Mice with deficiency in the endogenous LDL receptor gene. Develop atherosclerosis after a high fat diet	YES	Emiel van der Vorst evandervorst@ukaachen.de
LysM-Cre genetically engineered mouse strain widely used to delete or modify specific genes in myeloid cells	YES	Emiel van der Vorst evandervorst@ukaachen.de
Tie2-Cre Transgenic mouse line that expresses Cre recombinase under the control of the endothelial-specific Tek (Tie2) promoter and enhancer.	YES	Emiel van der Vorst evandervorst@ukaachen.de
Villin-Cre Villin-Cre is a transgenic mouse model that uses the villin 1 (Vil1) promoter to drive Cre recombinase expression in the epithelial cells of the small and large intestines, as well as the kidneys	YES	Emiel van der Vorst evandervorst@ukaachen.de