LDLr KO
Description:
Mice with deficiency in the endogenous LDL receptor gene. Develop atherosclerosis after a high fat diet
| Date Model Generated | 08-Sep-2026 |
|---|---|
| Randomized | |
| Open for Collab. | YES |
| Species | Mouse |
| Genetic Modification | Knock Out |
| Genetic Background | C57BL/6J |
| Method of Modification | Homologous Recombination in ES cells |
| Disease Model | Atherosclerosis |
| Zygosity | Homozygote |
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